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Nitrogen Protoxide

《英文msh詞典》Nitrogen Protoxide
[入口詞] Nitrogen Protoxide
[主題詞] Nitric Oxide
[藥動學(xué)] Free Radical Scavengers
[英文釋義] A free radical gas produced endogenously by a variety of mammalian cells,synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation,induces disaggregation of aggregated platelets,and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.